Studies on the Syntheses of 2 (1H)-Pyridone Derivatives. III. Synthesis of 6-Amino-2 (1H)-pyridones and Their Cyclization
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چکیده
منابع مشابه
Synthesis and phytotoxic activity of new pyridones derived from 4-hydroxy-6-methylpyridin-2(1H)-one.
Commercial dehydroacetic acid was converted into 4-hydroxy-6-methylpyridin-2(1H)-one (3), which was then condensed with several aliphatic aldehydes to produce seven new title compounds in variable yields (35-92%). Reaction of 3 with alpha,beta-unsaturated aldehydes resulted in the formation of condensed pyran derivatives 4g' and 4h'. A mechanism is proposed to explain the formation of such comp...
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Alkylation of quinolin-2(1H)-one (1) and its C(6) and C(7) substituted dervatives (OMe, OBn, and Cl) with 2-bromoacetophenone or chloroacetone under basic condition (K2CO3 in DMF) gave a mixture of N1and O2alkylated products with the former one as a major product. However, alkylation of 8-methoxy-, 8-benzyloxy-, and 8-chloroquinolin-2(1H)-ones under the same reaction conditions gave exclusively...
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Synthesis of 2-Amino-4hydroxy-1H-Pyrrole-3-Carbonitrile from Glycine Under Microwave Irradiation
Reaction of Glycin with Malononitrile afforded respective Pyrrole. Pyrrole is one of the heterocyclic compounds with very important biological activities. Heterocycles are extremely important because of their wide range of applications that goes from their use as pharmaceuticals and agrochemicals to dyestuffs and additives. In this view, it was proposed to synthesize pyrrole-3-carbonitrile deri...
متن کاملSynthesis of 2-Amino-4hydroxy-1H-Pyrrole-3-Carbonitrile from Glycine Under Microwave Irradiation
Reaction of Glycin with Malononitrile afforded respective Pyrrole. Pyrrole is one of the heterocyclic compounds with very important biological activities. Heterocycles are extremely important because of their wide range of applications that goes from their use as pharmaceuticals and agrochemicals to dyestuffs and additives. In this view, it was proposed to synthesize pyrrole-3-carbonitrile deri...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1979
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.99.8_788